5 resultados para HIV, primary resistance to antirretrovirales, virologic faulier, secondary resistance

em Repositório Científico da Universidade de Évora - Portugal


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Background: Knowing one’s own seropositivity status of HIV/AIDS is important. Seropositivity can be determined by a rapid HIV/AIDS test. Attitudes towards a rapid test of HIV/AIDS show a predisposition to perform the analysis. Objective: This study investigated, the attitudes of students and staff in a Portuguese university toward rapid HIV/AIDS test. Methods: In a convenience sample, the data was collected on campus in three consecutive years. A selfadministered structured questionnaire was used for data collection. A validated scale for Portuguese students was applied. A sample of 947 (86.3%) students and 150 (13.7%) teaching and non-teaching staff participated. The average age was 24.30 years-old (SD=8.64). Non-parametric tests were applied. Results: Attitudes of professors and non-teaching staff are more favorable in relation to the rapid test of HIV/AIDS, compared to students. Attitudes are also more favorable in the first year in which the study was conducted with both employees and students. The male students express more traditional attitudes. Students of nursing polo have expressed more favorable attitudes to the rapid test of HIV/AIDS. Conclusion: The attitudes towards rapid test of HIV/AIDS are generally favorable. It is necessary to conduct further research considering professors and other university staff. Improving favorable attitudes toward rapid HIV/AIDS test must be a positive fact for health.

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Introdução: Neste estudo será apresentado experimento sobre um programa de atividades físicas para diminuir os efeitos metabólicos da lipodistrofia, causada pela prescrição dos anti-retrovirais, medicamentos utilizados por portadores pelo vírus HIV\AIDIS. Objetivo: Investigar os benefícios dos exercícios físicos para indivíduos portadores do HIV\AIDS e combatendo doenças causadas pela lipodistrofia proveniente da terapia com anti-retrovirais. Metodologia: Foram 40 sujeitos divididos em grupo de exercício e grupo de controle. Os sujeitos participaram de palestra, exames e testes, tendo o grupo de exercício participado num programa de exército com duração de 24 semanas. As variáveis estudadas foram composição corporal, parâmetros bioquímicos e hemodinâmicos, e aptidão física e o questionário CEAT-VIH, versão em português do Brasil. Resultados: O programa de exercício apresentado foi positivo na composição corporal, parâmetros bioquímicos e hemodinâmicos e no questionário, CEAT-VIH, versão em português do Brasil. Na aptidão física o programa de exercício não obteve a resposta que esperávamos. Conclusão: O programa de exercício aplicado permitiu obter uma redução na massa corporal, IMC, glicose e colesterol, e melhoria ao nível da flexibilidade. Permitiu igualmente aumentar o cumprimento do seguimento da farmacologia prescrita pelos médicos; The Relevance of Physical Exercises for Individuals 30 to 50 years of Both Sexes Bearers of Acquired Immunodeficiency Syndrome (HIV \ AIDS) with Lipodystrophy Caused by the use of Anti-Retroviral. Summary: Introduction: In this study will be presented experiment on a physical activity program to decrease the metabolic effects of lipodystrophy, caused by the prescription of anti-retroviral drugs used by patients with HIV \ AIDIS. Objective: To investigate the benefits of exercise for people living with HIV subjects \ AIDS and combating diseases caused by lipodystrophy from therapy with antiretrovirals. Methods: 40 subjects were divided into exercise group and control group. The subjects participated in lecture, exams and tests, and the exercise group participated in an army program of 24 weeks duration. The variables studied were body composition, biochemical and hemodynamic parameters, and physical fitness and the CEAT-HIV questionnaire, version in Portuguese of Brazil. Results: The submitted exercise program was positive in body composition, biochemical and hemodynamic parameters and questionnaire, CEAT-HIV, version in Portuguese of Brazil. Physical fitness exercise program did not get the answer we expected. Conclusion: The applied exercise program yielded a reduction in body weight, body mass index, glucose and cholesterol, and improved level of flexibility. It has also increase compliance of following the prescribed pharmacology by doctors.

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Este estudo pretendeu pesquisar acerca da influência do cinema histórico de ficção na construção do conhecimento histórico de alunos de História A do Ensino Secundário. Foi realizado com uma turma do 10º ano de escolaridade de 20 alunos e foi antecedido de um estudo prévio. O trabalho baseou-se no visionamento do filme "O Gladiador" e na realização de fichas de trabalho: a "Ficha de Enquadramento Histórico do Filme", para contextualizar a época histórica em que decorria o filme; a "Ficha de Análise do Filme”, para recolha de dados e finalmente a "Ficha de Trabalho de Comparação entre Fontes Históricas e o Filme". As respostas fornecidas pelos alunos foram organizadas em categorias. Para as perguntas que pediam uma resposta mais directa e simples foram criadas três categorias: básica primária, básica secundária e definição elaborada. Para as perguntas que exigiam uma resposta mais complexa criaram-se cinco categorias: incoerente, básica primária, básica secundária, definição emergente e definição elaborada. As principais conclusões foram: a) o cinema de ficção desempenha um importante contributo na construção do conhecimento histórico dos alunos do ensino secundário; b) o visionamento de filmes de ficção na aula de História deve ser acompanhado com o confronto de fontes históricas para os alunos distinguirem ficção de conhecimento histórico; c) o cinema desempenha um papel muito importante no desenvolvimento das competências específicas de História do Ensino Secundário e do espírito crítico dos alunos; entre outras. / ABSTRACT: This study aimed to understand the influence of historical fiction movies in historical knowledge of students in History of Secondary Education. The study was conducted with a group of 20 students of the 1O th grade and was preceded by a preliminary study. The work was based on viewing the film Gladiator and on worksheets: A "Historical Background" to contextualize the historical era of the movie, the "The analysis of the Movie" to collect data and finally the “Comparison of Historical Sources and movie” worksheet to analyze distinguish fiction from historical knowledge. The responses given by students were categorized: for questions that asked for a more direct and simple answer were created three categories: Basic; Primary; Definition elaborated. For questions requiring a more complex answer were created five categories Incoherent; Basic; Primary; Emergent and Elaborated. The main conclusions were: a) the film fiction has an important contribution to historical knowledge of secondary school students, b) using films in history lessons should be accompanied with a comparison of historical sources for students to distinguish fiction from historical knowledge, c) the film plays an important role in the development of specific skills for the History of Secondary Education and the students' critical thinking, among others.

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We report an efficient methodology for the direct oxidative esterification of primary alcohols to diether-esters using pyridinium chlorochromate (PCC). Numerous studies were carried out to probe the reaction mechanism and at the same time optimize the reaction conditions. The reaction could be conducted with 1 equivalent of PCC and 1 equivalent of BF3 center dot OEt2. Indications based on literature precedent were that the reaction may proceed via a sequential alcohol oxidation to the aldehyde followed by a putative Cr or boron catalyzed Claisen-Tishchenko-type reaction. Using this efficient methodology, we synthesized a family of novel diether-esters in very good yields; some of these molecules were subsequently tested against both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). In addition, we also disclose a new synthetic strategy for the synthesis of lactam macrocycles with potential biological activity. This methodology included the regioselective borylation of the ester substrate and a subsequent Suzuki-Miyaura coupling to obtain the desired lactam macrocycle.

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Na divulgação de qualquer destino turístico é necessário ter em conta diversos fatores. Esta dissertação teve como principal objetivo analisar a procura e a oferta ao nível do turismo desportivo no concelho de Évora. Foi estudado o turismo desportivo no município de Évora, que é um dos maiores destinos turísticos da região Alentejo. Aplicando questionários de maneira a saber qual a opinião dos turistas relativamente a atividades desportivas praticadas neste destino. Foram ainda realizadas duas entrevistas a responsáveis da Câmara Municipal de Évora e ao Diretor de uma empresa de Animação Turística. A falta de estratégia no sector é evidenciada pelo facto dos visitantes não apresentarem como motivação primária a prática de atividades desportivas. Sendo o Turismo e o Desporto sectores económicos de grande importância em termos globais e locais, verificou-se que no concelho de Évora o Turismo Desportivo pode ser um grande agente de desenvolvimento em diversas áreas; Abstract: Sports Tourism in Évora Municipality The disclosure of any tourist destination should be taken into account several factors. This work aimed to analise the demand and supply in terms of sports tourism in Évora municipality. An investigation was made to the city of Évora, which is one of the biggest tourist destinations in Alentejo region, applying questionnaire in order to know the opinion of tourists with regard to sports activities practiced in this destination. They were also carried out two interviews with officials of the Municipality of Évora, and the Director of a Tourism Entertainment company. The lack of strategy in the sector is demonstrated by the fact that visitors do not present as the primary motivation to practice sports activities. Tourism and Sports are sectors of great importance in global and local economy, it was found that in Évora county, Sports Tourism can be a major agent of development in several areas.